Magnetic resonance imaging

GINYS-IDIBAPS-004
Emma Muñoz-Moreno
Cap de la plataforma
Magnetic resonance imaging (MRI) allows for visualization of organs and tissue in a non-invasive way, as well as its the characterization of their anatomical and functional properties. The IDIBAPS Magnetic Resonance Imaging Core Facility has two scanners for MR acquisition both in humans and in small animal o tissue samples. Besides, the facilty has an image laboratory with specific computer equipment and highly qualified staff specialized in research and development of analysis algorithms adapted to each project requirements. Together with image acquisition and analysis, the facility provides advisory service during the whole project: from project conception to the results discussion and interpretation.

Services

Magnetic resonance image acquisition in human and small animal. Among the image modalities provided by the facility, we can highlight:
  • Anatomical imaging
  • Diffusion imaging for microstructural and/or brain connectivity network analysis.
  • Resting-state and task-based functional imaging to identify patterns of cerebral activity.
  • Perfusion imaging to characterized blood flow in tissues.
  • Magnetic resonance spectroscopy, which allows for metabolite quantification.
  • Angiography to visualize the vasculature.
Magnetic resonance imaging in tissue samples, including:
  • High-resolution anatomical imaging.
  • Diffusion imaging for microstructure analysis and visualization.
Image processing and analysis. The image laboratory provides image analysis applying different techniques, including both standard methodologies and specific algorithms developed to fit the project requirements. Among the provided analysis, we can highlight:
  • Volumetric analysis: volumes of regions of interest, cortical thickness, etc..
  • Metabolite quantification
  • Anatomical and/or functional brain connectivity analysis.
  • Identification of brain networks associated to specific tasks.
  • Quantification of blood perfusion in the tissues.
  • 3D shape analysis for anatomical structures.
  • Radiomics, artificial intelligence based analysis.

Equipment

Clinical research unit (3 Tesla):
  • MR scanner for human imaging (3 Tesla Siemens Prisma Fit)
  • Visual and auditive stimulus presentation systems to perform functional MRI studies (Presentation, VisuaStim Digital)
  • Screen for visual stimulus projection.
  • Remote control to register the subject response in task-based functional MRI.

Experimental imaging unit (7 Tesla)

  • MR scanner for imaging small animal or tissue samples (7
    Tesla Bruker Biospec 70/30) equiped with specific coils for mice and rat imaging.
  • Anesthesia system by inhalation
  • Animal physiology monitoring system.

Image analysis and processing laboratory:

  • 2 workstation and 16 PCs.
  • Image analysis software: MatLab, LCModel, Freesurfer, FSL, itkSNAP, Synthetic MR, RAIM Alma

Staff

Cap de la plataforma
Emma Muñoz-Moreno | emunozm@recerca.clinic.cat | ORCID | PRC Page
Responsable àrea 3 Tesla
Especialista laboratori experimental
Xavier López-Gil | xavier.lopez@idibaps.org | ORCID | PRC Page
Científics d'imatge
Àngels Calvet | CALVETI@recerca.clinic.cat
Jose Carlos Pariente Zorrilla | pariente@recerca.clinic.cat
Marta Peña González | penai@recerca.clinic.cat
Alejandro Hinojosa | ahinojosa@recerca.clinic.cat
Técnics de radiologia
César Garrido | cgarrido@clinic.cat
Sandra Pineda | pineda@clinic.cat

Publications

Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms
Gisela Sugranyes, Elena de la Serna, Daniel Ilzarbe, Jose Carlos Pariente, Roger Borras, Soledad Romero, Mireia Rosa, Inmaculada Baeza, Maria Dolores Moreno, Miguel Bernardo, Eduard Vieta, Josefina Castro-Fornieles
Child Psychol. Psychiatr., 62: 780-789
Prognostic significance of infarct size and location: the case of insular stroke
Carlos Laredo, Yashu Zhao, Salvatore Rudilosso, Arturo Renú, José Carlos Pariente, Ángel Chamorro, Xabier Urra
Scientific Reports (2018), 8: 9498
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Christopher D Whelan, Andre Altmann, et al.
Brain (2018) 141(2), 391–408
M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease
Sara Fernández-García, Sara Conde-Berriozabal, Esther García-García, Clara Gort-Paniello, David Bernal-Casas, Gerardo García-Díaz Barriga, Javier López-Gil, Emma Muñoz-Moreno, Guadalupe Soria, Leticia Campa, Francesc Artigas, Manuel José Rodríguez, Jordi Alberch, Mercè Masana
eLife 9:e57017.
Brain connectivity during Alzheimer’s disease progression and its cognitive impact in a transgenic rat model
Emma Muñoz-Moreno, Raúl Tudela, Xavier López-Gil, Guadalupe Soria
Network Neuroscience (2020) 4 (2): 397–415.

INSTITUTE

IDIBAPS - Inst. d'Investigacions Biomèdiques August Pi i Sunyer

Rosselló, 149-153

08036 Barcelona http://www.clinicbarcelona.org/ca/idibaps

DOMAINS RIS3CAT

  • Education and knowledge generation system
  • Industrial system
  • Socio-sanitary system

CATEGORIES

  • INFORMATION TECNOLOGIES
    • Medical Imaging
  • STABLES AND ANIMAL EXPERIMENTATION CENTERS
    • Specialized animal experimentation
  • TECHNOLOGICAL EQUIPMENT

RATES AND ACCESS

Availability Level: High
Access Procedures:
Open

FACILITIES NETWORKS

EBRAINS – Shared digital brain research infrastructure for the EU
EBRAINS is a new digital research infrastructure, created by the EU-funded Human Brain Project, that collects a wide range of data and tools for brain-related research. EBRAINS will take advantage of the work done by the Human Brain Project teams in digital neuroscience, brain medicine and brain-inspired technology and take it to the next level.
Reach: Europe
Status: Active
CERCA - Ginys