CREBA (Applied Biomedical Experimental Research Center)
GINYS-IRBLL-002
Dr. Jorge Juan Olsina Kissler
Director del CREBA
Balaguer Street, 25138 Torrelameu, Lleida, Spain
CREBA (Centre for Applied Biomedical Experimental Research) is dedicated to translational biomedical research and continuous training of health professionals. Its main area of specialisation is porcine models, always following the 3Rs principle (reduction, refinement and replacement).
Located in the village of Torrelameu (Lleida), CREBA is well communicated with the main cities of the country, both by high-speed train and by road.
CREBA's facilities include an animal facility for pigs and four experimental operating theatres, with capacity for 8 operating tables for open surgery, laparoscopic surgery and other interventional techniques. It also has classrooms and annexes, as detailed in the following sections of this page.
Services
· Application of experimental procedures in pigs
· Veterinary anaesthesia
· Carrying out scientific dissemination activities
· Consultancy:
o Methodological
o Veterinary
o Surgical
o Writing of projects
o Presentation of results
o Writing of papers
· Processing of official authorisation for the use of laboratory animals
· Administrative management of activities
· Management of other logistic services:
o Transport
o Accommodation
Equipment
· ANIMAL FACILITIES for pigs. It has three lairage rooms, with capacity for 16, 16 and 4 animals, respectively (total capacity: 36 pigs weighing up to 50 kg). The facilities have a controlled environment, which complies with current regulations (Directive 63/2010 and Royal Decree 53/2013), and is registered as a user of laboratory animals (No. L9900008). The Centre is also authorised for the use of genetically modified animals.
· EXPERIMENTAL OPERATING THEATRES:
o 3 single operating theatres (with one surgical table each).
o 1 multiple operating theatre, with capacity for 5 surgical tables.
· SURGICAL EQUIPMENT and FACILITIES:
o Equipment for laparoscopic surgery (Karl Storz), with technology for fluorescence-guided surgery and 3D.
o Electrosurgery systems (monopolar and bipolar energy platforms).
o Cardiovascular and respiratory monitoring systems for large animals
o Monitors of various sizes (40″, 43″, 28¨and 24″), which can receive images from the laparoscopy system, from a zenithal camera over the surgery or from an environmental camera. Resources from a computer or mobile device can also be projected onto these screens.
o Surgical LED lights, with control of the colour temperature, brightness and amplitude of the spotlight.
o Audiovisual equipment that allows live viewing, recording and broadcasting of operations in high definition, both on a large screen in the operating theatre itself and remotely.
o Stainless steel surgical tables, with a surface area of 150 x 60 cm, in the form of 2 folding leaves (book type). Electrical, adjustable in height and inclination.
o Mobile columns with electrical, gas, video and audio connections and control of surgical lights.
o Centralised supply of gases (O2, CO2, and medical air) and vacuum.
o Surgical equipment, for open and laparoscopic surgery
· EQUIPMENT FOR IN VIVO IMAGING:
o Surgical C-arm flouroscopy system, for traumatology and angiography
o Radiological protections
o Surgical tables with radiolucent surface of 150 x 60 cm. Electrical, height adjustable
o Ultrasound scanner
· OTHER EQUIPMENT:
o Defibrillator
o Parasympathetic tone monitoring equipment (PTA)
o Perfusion pumps
· LABORATORY, equipped with:
o Analyzer of biochemical blood parameters
o Blood gas analyser
o Centrifuges for 5-15 ml tubes
o Plate shaker
o Roller shaker
o Cold preservation systems: +4 °C refrigerators, -20 °C freezers and -80 °C freezers
o Fume extraction cabinet for sample handling
· 3D PRINTING ROOM:
3D printer, Ultimaker brand, model S5.
· CLASSROOM (30 people) and MEETING ROOM (10 people), equipped with:
o Projector
o Projection screen
o Computers.
o Loudspeakers for speakers, presentations, or interlocutor connected from another room in CREBA, or from outside.
o Videoconference equipment
o Whiteboard
Staff
Dra. Sara Puy López | spuy@creballeida.org
| 973989084
Sara Castañé Castellví | tecnic@creballeida.org
| 973989084
Marta Farré Fola | mfarre@creballeida.org
| 973989084
Publications
Effects of negative-pressure therapy with and without ropivacaine instillation in the early evolution of severe peritonitis in pigs
Eur J Trauma Emerg Surg . 2021 Apr;47(2):597-606.
Eur J Trauma Emerg Surg . 2021 Apr;47(2):597-606.
A new minimally invasive porcine model for the study of intrahepatic bile duct dilatation
Surg Endosc . 2021 Jun;35(6):2817-2822.
Surg Endosc . 2021 Jun;35(6):2817-2822.
Measurement of Closure Forces During Abdominal Wall Closure as a New Parameter for Incisional Hernia Prevention: an Experimental Animal Study
J Surg 7: 1602.
J Surg 7: 1602.
