Bioinformatics
GINYS-IJC-005
Angelika Merkel
Unitat de Bioinformática
Edifici IJC
Ctra. de Can Ruti
Cami de les Escoles s/n
08916 Badalona
Barcelona, Spain
The IJC Bioinformatics Unit offers both the IJC and external researchers high-quality computational analysis services that cover all aspects of the project related to clinical and biological data. This includes experimental design and data analysis for next-generation microarray experiments and sequencing, statistical consulting, data integration, interpretation, and reporting, as well as software development and scientific database management.
Our team consists of qualified professionals with extensive experience in bioinformatics and research and experienced developers. The unit has access to high-performance computing resources and works closely with the Genomics and Single Cell units.
Services
The unit provides data processing and analysis for genomic, epigenomic and transcriptomic data microarrays and high performance sequencing
Microarrays
- Genome
- SNV panels
- QC, variant call
- Custom genotype grouping
- Epigenome
- DNA methylation (450K, EPIC) • QC, Standardization • Methylation call (beta / M values) • Cluster • Differential methylation (DM / DMR) • Gene + Association of regulatory elements
- Transcriptoma
- Gene expression matrices • QC, Normalization • Quantification • Cluster • Differential expression • Analysis of the enrichment of the genetic set microRNA matrices • QC, Standardization • Quantification • Cluster • Differential expression • Target prediction • MiRNA-gene expression correlation
High performance sequencing
Genome
- Whole genome sequencing (WGS)
- Exome sequencing
- QC, Alignment
- Call variant
Epigenome
- ChIP-seq, ATAC-seq, DNAse-seq
- QC, Alignment
- Call tap
- Differential binding
- Functional Analysis Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Analysis Bisulfite Sequencing (RRBS)
- QC, Cartography
- Methylation call
- Call variant
- Differential analysis (DMR / methyloma segmentation)
- Functional annotation
Transcriptoma
- RNAseq (poly +/-, total)
- QC, cartography • Quantification
- Alternative splicing
- Cluster
- Differential expression
- Analysis of the enrichment of the genetic set
Other consulting services
- Experimental design
- Statistical advice
- Analysis of workflow recommendations and tools
Formation
- Internships
- Seminars
- Workshops
Staff
