Biobank IDIBELL
GINYS-IDIBELL-010
The HUB-ICO-IDIBELL Biobank is a public, non-profit establishment that was created with the aim of managing and regulating the different collections of biological samples collected at the Bellvitge University Hospital (HUB), in the Duran i Reynals Hospital (ICO) and other associated centers, in accordance with current regulations (Law 14/2007, of 3 July on Biomedical Research and RD 1716/2011, of 18 November).
The HUB-ICO-IDIBELL Biobank has been authorized by the General Directorate of Health Planning and Research of the Department of Health of the Generalitat de Catalunya and is registered in the National Register of Biobanks of the Carlos III Health Institute in accordance with RD 1716/2011, which establishes the basic requirements for authorization and operation of biobanks for biomedical research purposes and the treatment of biological samples of human origin. The Biobank is part of the National Network of Biobanks.
Services
Activity and Objectives
The activities of the HUB-ICO-IDIBELL Biobank are to receive, process, store and distribute biological samples and their associated data for biomedical research, meeting technical and quality criteria, and guaranteeing ethical and legal requirements. Our main objectives are:
- Make biological samples and their associated data of high scientific interest available to the scientific community to contribute to the development of valuable knowledge in biomedical research.
- Manage and standardize existing sample collections on campus, and create new ones according to the most outstanding lines of research today.
- Promote quality practices and continuous improvement, complying at all times with ethical and legal requirements.
The HUB-ICO-IDIBELL Biobank offers researchers a wide range of services related to the processing, storage and management of samples. All Biobank procedures are performed following Standard Working Procedures (NTPs) established by biobank organizations (National Biobank Platform, ISBER and others).
Processing and cryopreservation services
- Prospective sample collection circuit
- DNA and RNA extraction and quantification
- Isolation and cryopreservation PBMCs
- Plasma, serum, urine and CSF processing
- Microtomy
- Storage at -80 ° C and -196ºC, traceability and sending of samples.
- Laser microdissection
Advice, registration and custody service
- Creation and management of new collections
- Guidance on ethical and legal aspects
- Management and processing of the registration with the competent authority of the project, research line or biobank collections
- Advice on the coding and transport of biological samples
- Preparation of informed consents
- Storage and traceability of samples from different collections
- Preparation of reports accrediting quality policies
- Preparation of reports of historical temperature records
- Sample search support in other national and international biobanks
Sample transfer service
- Receipt of applications
- Processing of documents to external committees (CCE and CEIC)
- Communication of the resolution to the applicant
- Preparation and support of the required documentation
- Preparation and sending of biological samples
Collections
- Tumor Bank Collection
- Neurological Tissue Bank Collection
- Surplus Pathological Anatomy Biopsies Collection
- Tumor Pathology Fluids Collection
- Lymphoma
- Breast cancer
- Hematology
- Meningeal carcinomatosis
- Non-Tumor Pathology Fluids Collection
- Inflammatory bowel disease
- Clostridium
- Nephrology
- Nephritis
- Kidney Transplant
- Multiple sclerosis
- Amyotrophic Lateral Sclerosis
- Immunological Minority Diseases
- Cardiology
- Retinal Dystrophy
- COVID19
- Organoids
Equipment
- 24 -80 ° C deep freezers equipped with double safety system. 24 hours of equipment monitoring.
- Nitrogen tank in the vapor phase (capacity 98,000 cryovials).
- Processing laboratory: biosafety booths, refrigerated centrifuges, triocular stereoscopic microscope, automatic cell counter, Nanodrop One, thermostatic bath, Histochill.
- Maxwell AS2000 extraction robot.
- LMD 7000 laser microdissector (Leica).
Staff
Publications
Conservation of aging and cancer epigenetic signatures across human and mouse.
Mol Biol Evol (2021)
Mol Biol Evol (2021)
Role of POLE and POLD1 in familial cancer.
Genet Med (2020) 22: 2089-2100.
Genet Med (2020) 22: 2089-2100.
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
Nature Neuroscience (2019) 22: 1258-1268.
Nature Neuroscience (2019) 22: 1258-1268.
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia.
Nature communications (2020) 1-11.
Nature communications (2020) 1-11.
Exploring Frequencies of Circulating Specific Th17 Cells against Myeloperoxidase and Proteinase 3 in ANCA Associated Vasculitis.
International journal of molecular sciences (2019) 20.23: 5820.
International journal of molecular sciences (2019) 20.23: 5820.
